Ddr1 therapeutic antibody
WebMar 21, 2024 · DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1) is a Protein Coding gene. Diseases associated with DDR1 include Spondylometaepiphyseal Dysplasia, Short Limb-Hand Type and Breast Cancer . Among its related pathways are GPCR Pathway and ERK Signaling . WebDDR1 Protein Overview. By screening a placenta cDNA library with a sequence common to several receptor tyrosine kinases, Johnson et al. (1993) cloned human DDR1, which they called DDR. The predicted protein contains 913 amino acids and has a calculated molecular mass of 105 kD. It has an N-terminal signal sequence, followed by extracellular ...
Ddr1 therapeutic antibody
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WebFeb 28, 2024 · DDR1 Antibody (D-10) is an IgG1 κ mouse monoclonal Discoidin Domain Receptor 1 (DDR1) antibody that detects m, r, and h DDR1 by WB, IP, IF and ELISA. 2 citations ... Not Intended for Diagnostic or Therapeutic Use. Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession Number Protein Accession Number … WebOct 1, 2014 · Potential therapeutic molecules that modulate human DDR1 activity were identified by screening the AnaptysBio Evolvable Library (ABEL) of fully human germline …
WebJan 13, 2024 · DDR1 is a single-pass receptor tyrosine kinase with an ECD which can be shed by matrix metalloproteases and binds collagen. DDR1’s main task is to facilitate the communication of cells with... Metrics - Barring the gates to the battleground: DDR1 promotes immune … WebAnti-DDR1 antibody (GTX25508) GeneTex Back Primary Antibodies Secondary Antibodies Antibody Panels ELISA Antibody Pairs & Kits Isotype Controls Proteins & Peptides Slides Lysates Serums & Plasmas Reagents Research Kits Research Tools Back Cancer Tumor Markers Neuroscience Cell Biology Metabolism Epigenetics …
WebMay 12, 2024 · We found that DDR1-overexpressing UM cells educated hepatic stellate cells (HSCs) to secret collagen I, which in turn ligated DDR1 to activate UM cells to release HSCs-activating soluble... WebDDR1 has been identified as a cancer-associated receptor tyrosine kinase that is highly expressed in several malignancies relative to normal tissues. Clinically approved multi …
WebDDR1 Antibody detects endogenous levels of total DDR1 protein. The antibody does not cross-react with other proteins of the DDR family. Species Reactivity: Human Source / Purification Polyclonal antibodies …
WebNov 3, 2024 · Membrane-untethered DDR1-ECD is sufficient to rescue the growth of Ddr1 -knockout tumours in immunocompetent hosts. Mechanistically, the binding of DDR1 … farm shop dawlishWebFeb 8, 2016 · Collectively, genetic and pharmacological observations demonstrate that DDR1 is a potential therapeutic target in KrasG12V lung adenocarcinoma. Additive effect of DDR1 and Notch inhibitors... farm shop dartfordWebAnti-Human DDR1 Therapeutic Antibody Manufactured by Gentaur. Gentaur is the biggest antibody manufacturer worldwide. Toggle menu. Welcome to WHY bio Systems! Station Cl. , Potters Bar EN6 1TL, United Kingdom 020 3393 8531; Sign in or Register; Compare ; Recently Viewed. Cart. Search. free seed packet templateWebddr1 Anti-Human DDR1 Recombinant Antibody (DDR1-ab3) This antibody has been found to exhibit high affinity and specificity for human DDR1, which is able to internalize DDR1 into cells quickly and kill cancer cells when conjugated to a drug such as a toxin. free seedlings to plantWebPhospho-DDR1 (Tyr792) Antibody recognizes endogenous levels of DDR1 protein only when phosphorylated at Tyr792. This antibody may cross-reacts with other tyrosine-phosphorylated RTKs. Species Reactivity: Human Species predicted to react based on 100% sequence homology: free seed packets for kidsWebTherapeutic antibodies are typically non-naturally occurring, or recombinant, antibodies specifically developed to treat human diseases by binding to certain proteins, and … free seed project 2021WebApr 6, 2024 · DDR1 Antibody (48B3) is an IgM κ mouse monoclonal DDR1 antibody (also designated DDR1 antibody or Discoidin Domain Receptor 1 (DDR1) antibody) suitable for the detection of DDR1 of human origin by IF, IHC (P) and FCM. DDR1 Antibody (48B3) is available as both conjugated and non-conjugated anti-DDR1 antibody forms. free seed project