WebFeb 16, 2016 · Cisplatin CCRT regimen comprised of hospital admission with intravenous cisplatin (100 mg/m 2 on days 1, 22, and 43 during radiotherapy) and is the standard care in our hospital. Patients are pre-hydrated 12 h prior to treatment, and posthydrated for 2 days with at least 3.5 L of 0.9% saline with 60 mmol/L of KCl and 30 mmol/L of MgSO 4 , … WebDosing Considerations. Verify any cisplatin dose exceeding 100 mg/m² per regimen. Pretreatment hydration: 1-2 L fluid infused for 8-12 hr before dose. May use concomitant amifostine to decrease...
Cisplatin Flashcards Quizlet
Established combination therapy (cisplatin, vinblastine, bleomycin) in patient with metastatic testicular tumors and with doxorubicin for metastatic ovarian tumors following appropriate surgical or radiation therapy. See more A heavy metal complex with platinum as central atom surrounded by 2 chloride atoms and 2 ammonia molecules in the cis chemical position. … See more Cell cycle-nonspecific, i.e., effective throughout the entire cell life cycle. Carcinogenicity has not been fully studied, but other compounds with similar action mechanisms and mutogenicity have been studied. See more History of hypersensitivity to cisplatin or other platinum-containing compounds; impaired renal function; myelosuppression; impaired hearing; history of gout and urate renal stones; hypomagnesia; … See more Web<45 Hold CISplatin or delay with additional IV fluids *Due to the curative intent of this chemotherapy regimen, in cases where CrCl falls between 45-59ml/min it may be appropriate to maintain dose of CISplatin but with extra hydration, longer infusion time and daily Creatinine measurements at the discretion of the prescribing consultant. sonic the hedgehog tika sumpter
Cisplatin Davis
WebSep 18, 2024 · Cisplatin can be used as monotherapy or as part of a multi-drug regimen. Patients should have proper hydration while monitoring … WebMonitor neuromuscular signs of electrolyte imbalances (hypocalcemia, hypokalemia, hypomagnesemia), including headache, lethargy, weakness, cramping, and muscle … WebCisplatin : Nursing Considerations 1. Give in AM 2. Pretreat with Zofran or Kytril 3. Push fluids before and after therapy 4. Monitor CBC, temp, s/s infection 5. Bleeding Precautions 6. MESNA = prevent HC 7. Baseline renal fx, hearing and pulmonary fx 8. High calorie, protein diet + smaller meals throughout the day Vincristine : Purpose small land yacht