Ceefourin-1
WebMay 24, 2024 · Ceefourin-1 additively cooperates with 6-MP to induce apoptosis in leukemic cells, but normal lymphoblast CRl-1991 showed resistance to both drugs. Conclusion: ceefourin-1 and 6-MP cooperates to trigger apoptosis in leukemic Jurkat cells, but the full mechanism needs to be elucidated in further works. In addition, our … WebSep 22, 2014 · Ceefourin 1 and Ceefourin 2 are claimed under Australian provisional patent application 2014902472. The licence agreement was facilitated by Bio-Link Australia, a life sciences commercialisation company. Related organisations Abcam, Cancer Research. By Children’s Cancer Institute and Abcam plc. 22 September 2014.
Ceefourin-1
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WebCeefourin 1: Selective MRP4 inhibitor: 4193: CP 100356 hydrochloride: P-gp inhibitor: 4646: Elacridar hydrochloride: P-gp and BCRP inhibitor: 2876: Fumitremorgin C: Inhibitor of BCRP-mediated multidrug resistance: 3241: Ko 143: Potent and selective BCRP inhibitor: 4169: KS 176: Selective BCRP inhibitor: 2338: WebMay 24, 2024 · Ceefourin-1 additively cooperates with 6-MP to induce apoptosis in leukemic cells, but normal lymphoblast CRl-1991 showed resistance to both drugs. Conclusion: ceefourin-1 and 6-MP cooperates to trigger apoptosis in leukemic Jurkat cells, but the full mechanism needs to be elucidated in further works. In addition, our …
WebFeb 13, 2004 · Ceefourin-1 is a specific MRP4/ABCC4 inhibitor with potential antileukemic activity. In this study, we evaluate the ability of ceefourin-1 alone or in combination with histamine, an approved antileukemic agent, to induce cell differentiation or apoptosis in human acute myeloid leukemic cells. We also examine ceefourin-1 toxicity in mice. WebA Biblioteca Virtual em Saúde é uma colecao de fontes de informacao científica e técnica em saúde organizada e armazenada em formato eletrônico nos países da Região Latino-Americana e do Caribe, acessíveis de forma universal na Internet de modo compatível com as bases internacionais.
Web10 mM * 1 mL in DMSO ￥550
WebMay 24, 2024 · Ceefourin-1 additively cooperates with 6-MP to induce apoptosis in leukemic cells, but normal lymphoblast CRl-1991 showed resistance to both drugs. Conclusion: ceefourin-1 and 6-MP cooperates to trigger apoptosis in leukemic Jurkat cells, but the full mechanism needs to be elucidated in further works. In addition, our …
WebCeefourin 1 is a selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC 50 = 2.6 μ M). Selective for MRP4 over P-gp, MRP1 and ABCG2. Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 (Cat. No. 2684). polygon guide ethermineWebBackground: Ceefourin-1 is a specific MRP4/ABCC4 inhibitor with potential antileukemic activity. In this study, we evaluate the ability of ceefourin-1 alone or in combination with histamine, an approved antileukemic agent, to induce cell differentiation or apoptosis in human acute myeloid leukemic cells. shania twain children\u0027s namesWebhuman platelets, Ceefourin-1 significan tly inhibited platelet aggregation by about 30-50% when ADP or collagen was used. as activating agents, respectively. Ceefourin-1 significantly lowered the ADP-induced activation of integrin . b. 3, a. IIb. indicated by binding of FITC-fibrinogen (about 50% reduction at 50 . m. M Ceefourin-1), and ... polygon group incWebSep 22, 2014 · Abcam entered into a license, supply, and distribution agreement with Children’s Cancer Institute for multidrug resistance protein 4 (MRP4/ABCC4) inhibitors Ceefourin™ 1 and Ceefourin 2, for ... shania twain christmas albumWebHowever, Ceefourin-1 resulted in no further attenuation of aggregation in the Mrp4-deficient platelets, indicating that the effect of Ceefourin-1 on platelet function is only due to MRP4 inhibition. Ceefourin-1 also reduced platelet aggregation after stimulation with ADP only in the WT platelets ( Online Supplementary Figure S3 ). shania twain citi presale codeWebWe studied the antiproliferative effect and the overall cAMP response of three MRP4 inhibitors, probenecid, MK571, and ceefourin-1 in PDAC in vitro models. Moreover, MRP4-specific silencing in PANC-1 cells reduced cell proliferation ( P < 0.05), whereas MRP4 overexpression in BxPC-3 cells significantly incremented their growth rate in culture ... shania twain christmas cardWebCeefourin 1 is a selective MRP (multidrug resistance-associated protein) 4 inhibitor (IC 50 = 2.6 μ M). Selective for MRP4 over P-gp, MRP1 and ABCG2. Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 (Cat. No. 2684). shania twain christmas album 2020